ANTIMICROBIAL ACTIVITY OF THREE MEDICINAL PLANTS

  • Nizar Sirag Department of Chemistry and Pharmacognosy, Faculty of Pharmacy, University of Gezira, Sudan
  • Sitelbanat Yassin Department of Pharmaceutics, Faculty of Pharmacy, University of Gezira, Sudan
  • Mirghani A Yousif Department of Pharmaceutics, Faculty of Pharmacy, University of Gezira, Sudan.

Abstract

Background: Medicinal plants have been traditionally used for different kinds of ailments including infectious diseases.


Objectives: The present work was undertaken to investigate the antimicrobial activity of three plants used in folk medicine.


Methods: Plant extracts of (Quercus infectoria, Glycyrrhiza glabra and Lepidium virginicum) were in vitro tested against four bacterial strains and one type of fungi for their antimicrobial activities by using well diffusion techniques.


Results: The ethanolic extracts of these plants showed varying results. Quercus infectoria was found to possess the highly marked antibacterial activity against both E. coli and Staphylococcus aureus while Glycyrrhiza glabra exhibited a significant antibacterial effect against Pseudomonas aurginosa. Lepidium


virginicum produced antibacterial activity against E.coli. Both Quercus infectoria and Lepidium virginicum caused a considerable antifungal effect, while Glycyrrhiza glabra devoid of such antifungal activity.


Conclusion: The three tested plant extracts could be considered as potential sources of new antimicrobial agents. Further researches should be made to isolate compounds responsible for antimicrobial activities.

References

1. Evans, C.W (1992). Trease and Evans. Pharmacognosy, (13 edition) Bailliere Tindall, London 758-762.
2. Ali, B.H; Bashir, A.K, and Tanira, M.O.H (1995). Anti-inflammatory, antipyretic and analgesic effects of Lawsonia inermis in rats. Pharmacology 51:356-363.
3. Boji, H; Steven, J; Kenneth, A and Bachmann, A (2005). A nationwide survey on bacterial respiratory infections in ambulatory patients. Journal of clinical epidemiology. 58:414-420.
4. Natarajan, V; Venugopal, PV, and Menon, T (2003). Effect of Azadirachta indica on the growth pattern of dermatophytes. Indian journal of medicine and microbiology. 21:98-101.
5. Goun, E; Cunningham, D; Chu, C and Mile, D (2003). Antibacterial and antifungal activity of Indonesian ethno medical plants. Fitoterapia.74:592-596.
6. Misra, SK and Sahu, HC (1977). Screening of some indigenous plants for antifungal activity against dermatophytes. Indian journal of pharmacology 9:269-272. 7. Almaqbool, AZ; Bashir, AK and Salih, AKM (1988). Antimicrobial activity of certain Sudanese plants used in Folkloric Medicine. Fitoterapia 56:59-62.
7. Iqbal, Z; Shabeen, H and Sheraz, B (2002). Antifungal properties of some indigenous plants from Peshawar Valley. Asian journal of plant science .1:708-709.
8. Khattak, SG; Gilani, SN and Ikram, M (1985). Antipyretic studies on some indigenous Pakistani medicinal plants. Journal of ethnopharmacology .14:45-52.
9. Elie, K; Vatche, K; Rbih, S and Salma, N. (2004). Screening of selected indigenous plants of Lebanon for antimicrobial activity. Journal of ethnopharmacology. 93:1-7.
10. Doughari, J.H; Pukuma, M.S and De, N (2007). Antibacterial effects of Balanites aegyptica and Moringa oleifera on Salmonella typhi. African journal of Biotechnology. 6(19)2212-2215.
11. Jinga, P; Nehal, K and Sumitra, C (2006). Evaluation of antibacterial activity and phytochemical analysis of Bauhinia variiegata bark. Journal of biomedical research .9(1)53-56.
12. Samo Andrensek; Breda Simvnovska and Irena Vovk (2004). Antimicrobial and Antioxidative enrichment of Oak (Quercus robur), International Journal of Food Microbiology: 92; 181- 187.
13. Ayfer, S and Turgey, A (2003). Antimicrobial activities of various medicinal and commercial plant extracts. Department of Biology, Faculty of Arts and Science, Imam University, Kahramanmaras, Turkey.
14. Gulluce, M; Sengul, M and Karaman, I (2008). Antimicrobial effect of Quercus. Journal of Phytotherapy Research: 18: (3): 208-211.
15. Vivek , K; Gupta; Atiya Fatima ; Uzma , F (2008). Antimicrobial activity of Glycyrrhiza glabra root. Journal of Ethnopharmacology: 116: (2): 377-380.
16. Gislene, G.F; Nascimento, J.L and Silva, L (2000). Antibacterial activity of plant extracts and phytochemicals on antibiotic resistant bacteria. Brazilian journal of microbiology 31:247-256.
17. Bassari, D.F and Fan, S.H (2004). The potential of aqueous and acetone extracts of galls of Quercus infectoria as antibacterial agents. Indian journal of pharmacology 37(1):26-29.
18. Supayang, P; Sasitorn, C and Sakol, S (2008). Quercus infectoria. Pharmaceutical biology. 46(6):367-372
Published
2009-12-01
How to Cite
SIRAG, Nizar; YASSIN, Sitelbanat; YOUSIF, Mirghani A. ANTIMICROBIAL ACTIVITY OF THREE MEDICINAL PLANTS. Gezira Journal of Health Sciences, [S.l.], v. 5, n. 2, dec. 2009. ISSN 1810-5386. Available at: <http://37.60.236.48/index.php/gjhs/article/view/439>. Date accessed: 03 june 2026.
Citation Formats
Issue
Vol 5 No 2 (2009)
Section
Articles