RARE PRESENTATION OF ACUTE MYELOID LEUKAEMIA IN A SUDANESE CHILD
Abstract
Classically, children with acute leukaemia present with symptoms and signs related to infiltration of the bone marrow by leukaemic cells, such as fever, pallor and fatigue, cutaneous and mucosal bleeding and bone pain. Also anorexia and weight loss. This is a case of acute myeloid leukaemia (AML.) which presented with tongue bleeding and then part of the tongue separated completely from the rest of the tongue and it fell from his mouth, few days later it regenerated to a normal tongue. Few days after regeneration of the right side of the tongue, the same previous scenario occurred in the left side, and then regenerated to normal size. This indicates an unusual presentation of AML.
References
Krstovski N, Janic D, Dokmanovic L. Childhood acute myeloid leukaemia. Journal of Pediatric Sciences 2010; 2: e23
2. Deschler B, Lübbert M. Acute myeloid leukemia: epidemiology and etiology. Cancer. 2006; 107: 2099-107.
3. T Sharma T; Grewal J; Gupta S; and Murray P I. Ophthalmic manifestations of acute leukaemias: the ophthalmologist's role. Eye 2004; 18: 663–672.
4. Choi, S I and Simone, J V. Acute nonlymphocytic leukemia in 171 children. Paediatrics Blood & Cancer 2006; (2) 2: 119–146.
5. Rubnitz JE, Gibson B, Smith FO. Acute myeloid leukemia. Pediatr Clin North Am.2008; 55: 21-51.
6. Hutspardol, S H. Common Problems in Pediatric Oncology.
Available from: http://elearning.medicine.swu.ac.th/pedia/wp-content/uploads/2009/06/oncology17may2010.pdf
7. Kingsley EC, Durie BGM, Garewal HS: Acute promyelocytic leukemia. West J Med 1987; 146: 322-327.
8. Stein-Wexler R, Wootton-Gorges SL, West DC. Orbital granulocytic sarcoma: an unusual presentation of acute myeloid leukaemia. Pediatr Radiol 2003; 33:136-9.
9. Peter B. Langmuir, Richard Aplenc, Beverly J. Lange. Acute myeloid leukaemia in children. Clinical Haematology 2001; 14: 77-93.
10. Miller RW. Special susceptibility of the child to certain radiation-induced cancers. Environ Health Perspect. 1995; 103: 41-4.
11. O.M. KoriechK, F.Z. Al-Dash. Skin and bone necrosis following ecthyma gangrenosum in acute leukaemia: report of three cases. Clinical and Experimental Dermatology 2006;13: 78 – 81.
12. Ferri E, Minotto E C, Ianniello F, Cavaleri S, Armato E, and Capuzzo P. Maxillo-ethmoidal chloroma in acute myeloid leukaemia: Case report. Acta Otorhinolaryngol Ital. 2005; 25(3): 195–199.
13. Papamanthos M K, Kolokotronis A E, Skulakis H E, Angela-Monika A. Fericean A A, Zorba M T and Matiakis A T. Acute Myeloid Leukaemia Diagnosed by Intra-Oral Myeloid Sarcoma. A Case Report. Head Neck Pathol. 2010; 4(2): 132–135.
14. Greenburg M and Glick M. Burket’s oral medicine diagnosis and treatment.
10th ed. BC Decker Inc.; 2003. p.443-8.
15. McKenna SJ. Leukemia. Oral Surg Oral Med Oral Pathol Oral Radiol
Endod. 2000; 89: 137-9.
2. Deschler B, Lübbert M. Acute myeloid leukemia: epidemiology and etiology. Cancer. 2006; 107: 2099-107.
3. T Sharma T; Grewal J; Gupta S; and Murray P I. Ophthalmic manifestations of acute leukaemias: the ophthalmologist's role. Eye 2004; 18: 663–672.
4. Choi, S I and Simone, J V. Acute nonlymphocytic leukemia in 171 children. Paediatrics Blood & Cancer 2006; (2) 2: 119–146.
5. Rubnitz JE, Gibson B, Smith FO. Acute myeloid leukemia. Pediatr Clin North Am.2008; 55: 21-51.
6. Hutspardol, S H. Common Problems in Pediatric Oncology.
Available from: http://elearning.medicine.swu.ac.th/pedia/wp-content/uploads/2009/06/oncology17may2010.pdf
7. Kingsley EC, Durie BGM, Garewal HS: Acute promyelocytic leukemia. West J Med 1987; 146: 322-327.
8. Stein-Wexler R, Wootton-Gorges SL, West DC. Orbital granulocytic sarcoma: an unusual presentation of acute myeloid leukaemia. Pediatr Radiol 2003; 33:136-9.
9. Peter B. Langmuir, Richard Aplenc, Beverly J. Lange. Acute myeloid leukaemia in children. Clinical Haematology 2001; 14: 77-93.
10. Miller RW. Special susceptibility of the child to certain radiation-induced cancers. Environ Health Perspect. 1995; 103: 41-4.
11. O.M. KoriechK, F.Z. Al-Dash. Skin and bone necrosis following ecthyma gangrenosum in acute leukaemia: report of three cases. Clinical and Experimental Dermatology 2006;13: 78 – 81.
12. Ferri E, Minotto E C, Ianniello F, Cavaleri S, Armato E, and Capuzzo P. Maxillo-ethmoidal chloroma in acute myeloid leukaemia: Case report. Acta Otorhinolaryngol Ital. 2005; 25(3): 195–199.
13. Papamanthos M K, Kolokotronis A E, Skulakis H E, Angela-Monika A. Fericean A A, Zorba M T and Matiakis A T. Acute Myeloid Leukaemia Diagnosed by Intra-Oral Myeloid Sarcoma. A Case Report. Head Neck Pathol. 2010; 4(2): 132–135.
14. Greenburg M and Glick M. Burket’s oral medicine diagnosis and treatment.
10th ed. BC Decker Inc.; 2003. p.443-8.
15. McKenna SJ. Leukemia. Oral Surg Oral Med Oral Pathol Oral Radiol
Endod. 2000; 89: 137-9.
Published
2011-06-01
How to Cite
MUSA, ShamsElFalah et al.
RARE PRESENTATION OF ACUTE MYELOID LEUKAEMIA IN A SUDANESE CHILD.
Gezira Journal of Health Sciences, [S.l.], v. 7, n. 1, june 2011.
ISSN 1810-5386. Available at: <http://37.60.236.48/index.php/gjhs/article/view/299>. Date accessed: 03 june 2026.
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