Effect of Anogeissus leiocarpus leaf extract on blood glucose level in rats
Abstract
The effect of the methanolic leaf extract of Anogeissus leiocarpus was studied in normal wister albino rats pretreated with a loading dose of glucose to explore its hypoglycaemic activity. Significant hypoglycemic effect was observed (P< 0.05) at a dose of 100 mg/kg B.W. 2 hours following treatment. At a dose of 200mg/Kg B.W. the plant extract showed no significant change in blood glucose level, while at a dose of 400mg/kg B.W. there was hyperglycaemic effect 2 and 4 hours following/after treatment.
References
Reference:
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1. Broun A, Massey R. flora of the Sudan. Published with the consent of the Sudan Goverment 1929; Pp112.
2. Nduji A, Okwut S. J. phytochem 1998; 48(2): 55-58.
3. Anderson B, Howlett J, Mcuaba C. phytochem 1987; 20; 837.
4. Aspinall G, christensen T. J. of chem soc 1961; 34:61.
5. Akande J, Yamamote K. J of tropical. forest products 1998; 4(2): 146-152.
6. Taiwo O, XuH, lee S, and Xu Hx. phytother. Res 1999; 13(8): 675-676.
7. Konuklugil B, Deniz G, Yildi O, Senoz S, Saygi S. Fitoteropia 1996; LXVIII (1): 39-41.
8. Huralikuppi, J.C.; Christopher, A.B. and Stephen, PM. Phytotherapy Research; 1991, 5(5): 217-223.
9. Rodriguez, C.J.; Loyola, J. and Schmeda, H.G. Phytotherapy Research; 1992, 6 (1): 47-49.
Published
2007-01-01
How to Cite
ABUBAKR, muzdalifa et al.
Effect of Anogeissus leiocarpus leaf extract on blood glucose level in rats.
Gezira Journal of Health Sciences, [S.l.], v. 3, n. 1, jan. 2007.
ISSN 1810-5386. Available at: <http://37.60.236.48/index.php/gjhs/article/view/213>. Date accessed: 03 june 2026.
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