Prevalence of H.pylori in the Arab world
Abstract
Aim: To investigate prevalence of Helicobacter pylori (H. pylori) among healthy asymptomatic and symptomatic patients in the Arab world. Where H.pylori infection constitutes a real heath problem.
Methods: A computerized comprehensive English language literature search of Pub Med, Scopus, and Google scholar was carried out in April 2016, evaluating the prevalence of H.pylori in the Arab countries.
Results In the electronic search, a total of 100 papers were initially identified. And after evaluating the titles, abstracts and full text of relevant articles.44 papers were included in this review
Conclusion: This review demonstrated high prevalence of H.pylori infection among symptomatic and asymptomatic people of the Arab world, immediate intervention should be made regarding identification, eradication and prevention of this bacterium.
الهدف:هدفت هذه الدراسة لدراسة معدل انتشار الملتوية البوابية بين المرضى الذين يعانون أعراض و الا صحاء في العالم العربي. حيث تشكل بكتيريا الملتوية البوابية مشكلة صحية حقيقية
الطريقة: تم إجراء بحث محوسب شامل في اللغة الإنجليزية لأبحاث بوب ميد، سكوبوس، و غوغل سشولار في أبريل 2016، لتقييم معدل انتشار بكتيريا الملتوية البوابية في البلدان العربية .النتائج: بعد البحث الالكترونى تم الحصول على 100 ورقة وبعد تقييمها 44 ورقة وجدت مناسبة لتتضمن فى دراسة المراجعة هذه الخلاصة: هذه المراجعة أظهرت ارتفاع معدل انتشار بكتيريا الملتوية البوابية بين الناس سواء كانوا يعانون من أعراض او بدون أعراض في العالم العربي، وينبغي بذل التدخل الفوري فيما يتعلق بتحديد والاستئصال والوقاية من هذه البكتيريا
References
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2. (2). Sachs G, Wen Y, Scott DR. Gastric infection by Helicobacter pylori. Curr Gastroenterol Rep 2009; 11(6): 455-461.
3. (3). Suerbaum S, Michetti P. Helicobacter pylori infection. N Engl J Med 2002; 347: 1175-1186.
4. (4).Goodman K J. and Cockburn M. "The role of epidemiology in understanding the health effects of Helicobacter pylori". Epidemiology 2001;12 (2): 266–271.
5. (5). Ruggiero P. Helicobacter pylori infection: What’s new. Curr Opin Infect Dis 2012; 25: 337-344.
6. (6). Mbulaiteye SM, Hisada M, El-Omar EM. Helicobacter pylori associated global gastric cancer burden. Front Biosci 2009; 14:1490-1504.
7. (7). Salih BA. Helicobacter pylori infection in developing countries: the burden for how long. Saudi J Gastroentrol 2009; 15(3): 201-207.
8. (8). Malfertheiner P. The intriguing relationship of Helicobacter pylori infection and acidsecretion in peptic ulcer disease and gastric cancer. Dig Dis 2011; 29(5): 459-464.
9. (9).Malaty HM, Nyren O. Epidemiology of Helicobacter pylori infection. Helicobacter 2007; 8: 8-12.
10. (10). Vale FF, Vítor JM. Transmission pathway of Helicobacter pylori: does food play a role in rural and urban areas? Int J Food Microbiol 2010; 138(1-2): 1-12.
11. (11). Magalhães DM, Luzza F. Epidemiology of Helicobacter pylori infection. Helicobacter 2006; 11(Suppl 1): S1-S5.
12. (12). Olokoba A, Gashau W, Bwala S, Adamu A, Salawu FK. Helicobacter pylori infection in Nigerians with dyspepsia. Ghana Med J 2013; 47(2): 79-81.
(13). Go MF. Review article: natural history and epidemiology of Helicobacter pylori infection. Aliment Pharmacol Ther 2002; 16
13. (14). Cheng H, Hu F, Zhang L, Yang G, Ma J, Hu J, et al . Prevalence of Helicobacter pylori infection and identification of risk factors in rural and urban Beijing, China. Helicobacter 2009;14:128-33
14. (15).MalatyHM.EpidemiologyofHelicobacterpylori infection.Be stPra Res Clin Gastroenterol 2007;21:205-14.
15. (16).Rowland M, Daly L, Vaughan M, Higgins A, Bourke B, Drumm B. Age-specific incidence of Helicobacter pylori . Gastroenterol 2006;130:65-72.
16. (17). Marshall JK, Armstrong D, O′Brien BJ. Test and treat strategies for Helicobacter pylori in uninvestigated dyspepsia: a Canadian economic analysis. Can J Gastroenterol 2000;14:379-88.
17. (180. Fischbach W, Malfertheiner P, Hoffmann JC, Bolten W, Kist M,Koletzko S, et al. Helicobacter pylori and gastroduodenal ulcer Disease. Dtsch Arztebl Int 2009; 106(49): 801-808.
18. (19). Daw MA, Shawky S. Going beyond the curriculum to promote medical education and practice (multiple letters)Saudi Medical Journal. 2002;23(1):116–117. [PubMed]
19. (20). Eshraghian A. Epidemiology of Helicobacter pylori infection among the healthy population in Iran and countries of the Eastern Mediterranean Region: A systematic review of prevalence and risk factors. World Journal of Gastroenterology : WJG. 2014; 20(46):17618-17625.
20. 21.Marie MA. Seroprevalence of Helicobacter pylori Infectionin Large Series of Patients in an Urban Area of Saudi Arabia.Korean J Gastroenterol 2008; 52: 226-229
21. (22). Khan ,M A, Ghazi HO. Helicobacterpylori infection in asymptomatic subjects in Makkah, Saudi Arabia. J Pak Med Assoc. 2007;57:114–7.
22. (23) . Hanifi M I, Mohamed A,M. Helicobacterpylori infection: seroprevalence and predictors among healthy individuals in Al Madinah, Saudi Arabia. J Egypt Public Health Assoc. 2013;88:40–5. [PubMed].
23. (24). Bakri M M. Prevalence of Helicobacter pylori infection and the incidence ofureA and clarithromycin resistance gene 23S rRNA genotypes status in Saudi Arabia. Saudi Journal of Biological Sciences2013; 20 (1): 75–78.
24. (25). Al Faleh, F. Z., Ali, S., Aljebreen, A. M., Alhammad, E. and Abdo, A. A. Seroprevalence Rates of Helicobacter pylori and Viral Hepatitis A among Adolescents in Three Regions of the Kingdom of Saudi Arabia: Is There Any Correlation?. Helicobacter 2010; 15: 532–537.
25. (26). Telmesani AM .Helicobacter pylori: prevalence and relationship with abdominal pain in school children in Makkah City, western Saudi Arabia. Saudi J Gastroenterol. 2009 Apr; 15(2):100-3.
26. (27). Alazmi WM, Siddique I, Alateeqi N, Al-Nakib B. Prevalence of Helicobacter pylori infection among new outpatients with dyspepsia in Kuwait. BMC Gastroenterol. 2010;10:14. doi: 10.1186/1471-230X-10-14.
27. 28.Al Qabandi A, Mustafa AS, Siddique I, Khajah AK, Madda JP, Junaid TA. Distribution of vacA and cagA genotypes ofHelicobacter pylori in Kuwait. Acta Trop 2005; 93: 283-288
28. (29). Al-Enezi SA, Alsurayei SA, Aly NY, Ismail AE, Ismail WA, Al-Brahim N, El-Dousari A
29. Endoscopic nodular gastritis in dyspeptic adults: prevalence and association with Helicobacter pylori infection.Med Princ Pract. 2010; 19(1):40-5.
30. (30). Alwahaibi N.Y, Almahrooqi B.M, Alrawahi S.A. The prevalence of helicobacter pylori and gastritis in Oman. J Dig Endosc 2013;4:29-32
31. (31). Al-Balushi M.S, Al-Busaidi JZ, Al-Daihani MS, Shafeeq MO, Hasson SS. Sero-prevalence of Helicobacter pylori infection among asymptomatic healthy Omani blood donors. Asia Pac J Trop Dis.2013;3:146–149.
32. (32). Huda Z. Al-Shami. Prevalence of Helicobacter pylori infection among patients underwent upper gastrointestinal tract endoscopy in Sana’a major hospitals; Thesis in MSc, Faculty of Medicne, Sana’a University, Yemen 2002.
33. (33). Al-Makdad A M, Al-Dholaee M H, Thabet A A K, Al-Haimi M A, Balfaqih O S, Al-Hadad A M.
34. Prevalence of Helicobacter Pylori Infection in Yemeni Patients 2013;7
35. (34).Gunaid AA, Hassan NA, Murray-Lyon IM. Recurrence of Helicobacter pylori infection 1 year after successful treatment: prospective cohort study in the Republic of Yemen. Eur J Gastroenterol Hepatol. 2004; 16 (12):1309-14.
36. (35). Hashim A M, Abualsel A,.Mostafa N R, Obaid J,. The Prevalence of Helicobacter Pylori Infection in Obese and Non-Obese Subjects Attending the Endoscopy Unit. Bahrain Med Bull 2015; 37(4): 234 – 236
37. (36). Fakhro AR, Fateha Bel D, Amin Farid IM, Jamsheer HM. The association between Helicobacter pylori infection and lymphoid reaction in patients suffering from dyspepsia in Bahrain. Saudi J Gastroenterol.1999;5:129–133.
38. (37). Bener A, Uduman SA, Ameen A, Alwash R, Pasha MA, Usmani MA, AI-Naili SR, Amiri KM. Prevalence of Helicobacter pylori infection among low socio-economic workers. J Commun Dis. 2002;34:179–184
39. (38). Bener A, Adeyemi EO, Almehdi AM, Ameen A, Beshwari M, Benedict S, Derballa MF. Helicobacter pylori profile in asymptomatic farmers and non-farmers. Int J Environ Health Res. 2006;16:449–454
40. (39). Adeyemi EO, Fadlalla H, al-Homsi M, et al. Clinicopathological assessment of gastric biopsy samples of patients with Helicobacterpylori infection--metronidazole resistance and compliance problems in the United Arab Emirates. Ital J Gastroenterol. 1992;24:436–9.
41. (40). Sebastian M, Chandran VP, Elashaal YI, Sim AJ. Helicobacterpylori infection in perforated peptic ulcer disease. Br J Surg. 1995;82:360–2.
42. (41). Latif A,. Azadeh B.Helicobacter Pylori Gastritis in Qatar A Clinico-Histopathological Study Qatar Med. J.. 2002 ;11:. 2.
43. (42). Bani-Hani KE, Hammouri SM. Prevalence of Helicobacter Pylori in Northern Jordan: Endoscopy based study. Saudi Med J 2001; 22: 843-7.
44. (43).Nimri L, Bani-hani KE, Matalka I, Ibrahim M. Clinical Relevance of vacA, cagA, and iceA Genotypes of Helicobacterpylori. 2011. Available atURL: https://www.webmedcentral.com/wmcpdf/Article-WMC002515.pdf
45. NM, ,,sein NR, Robinson K, Atherton JC. A study of agespecificHelicobacter pylori seropositivity rates in Iraq. Helicobacter 2008; 13: 306-307
46. (45). Hussen BM, Qader S S, AhmedH F , Ahmed SH. The Prevalence of Helicobacter pylori among University Students in Iraq.2013:6(8); 5019-5023.
47. (46). Alsaimary I, Al-Sadoon M, Jassim A, Hamadi S. Clinical Findings and Prevalence of Helicobacter Pylori in Patients with Gastritis B in Al-Basrah Governorate.
48. OMJ.2009: 24;208-211.
49. (47).Naous A1, Al-Tannir M, Naja Z, Ziade F, El-Rajab M. Feco-prevalence and determinants of Helicobacter pylori infection among asymptomatic children in Lebanon. J Med Liban. 2007;55(3):138-44.
50. (48). Naja F1, Nasreddine L, Hwalla N, Moghames P, Shoaib H, Fatfat M et al. Association of H. pylori infection with insulin resistance and metabolic syndrome among Lebanese adults. Helicobacter. 2012 ;17(6):444-51.
51. (49). Abu-Mugesieb RM, Elmanama AA, Mokhallalati MM. Risk Factors Associated with Helicobacterpylori Infection in Gaza, Palestine. 2007. Available at: URL:http://library.iugaza.edu.ps/thesis/74054.pdf
52. (50). Muhsen Kh, Athamna A, Athamna M, Spungin-Bialik A, Cohen D. Prevalence and risk factors of Helicobacterpylori infection among healthy 3- to 5-year-old Israeli Arab children. Epidemiol Infect.2006;134:990–6.
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Published
2018-06-01
How to Cite
ABDALLAH, TajEldin M et al.
Prevalence of H.pylori in the Arab world.
Gezira Journal of Health Sciences, [S.l.], v. 14, n. 1, june 2018.
ISSN 1810-5386. Available at: <http://37.60.236.48/index.php/gjhs/article/view/1275>. Date accessed: 03 june 2026.
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